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Products: µDISS
    µDISS Small Volume Dissolution Profiling

  • Ideal for characterising intrinsic dissolution in early-phase discovery/development where large quantities are not available
  • µDISS can generate detailed dissolution profiles in minutes in volumes as small as 2ml
  • No removal of sample during measurement required
  • Up to 6 channels can be studied simultaneously
  • Two options:- Micro, for volumes from 5ml to 20ml Ultra-micro, for volumes from 2ml to 4ml

Current Applications

  • Rank-order compounds by intrinsic dissolution
  • Detect polymorphic changes
  • Follow stability-time profiles

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Fig1. µDISS Command Software displaying 6-channel in situ dissolution and solubility of Phenazophyridine.HCl in the small volume apparatus  Fig2. SigmaPlotTM (SSI) software displaying the dissolution curve of Phenazopyridine.HCl in HEPES buffer at pH 7.4. The inset is an expanded view of the first three minutes of data collocation. 
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